Unfortunately, pretreatment evaluation could not identify the nonresponders beforehand. CEUS could be used to visualize the effects of high-intensity focussed ultrasound and hormonal therapy for prostate cancer with success, and identified patients with an early relapse. A combined approach offered the highest detection rate. Visualization of the tumour enabled better detection targeted biopsies lead to fewer biopsies per session without loss of detection rate. Studies showed that prostate cancer could be visualized and localized in up to 78%. Various techniques were developed and researched during the period of this program. This paper describes and combines the results of these studies. In the period 2002–2006, research in four European centres regarding CEUS of the prostate was coordinated in a combined program. To determine the value of contrast-enhanced ultrasound (CEUS) in the detection, localisation, and follow-up of treatment for prostate cancer. ![]() Studies have shown promising results for the diagnosis of prostate cancer for various imaging techniques however, the exact value of each technique is still unclear. Since tumour growth is associated with changes in vascularisation, this modality is under research for imaging of various tumour types. ![]() Contrast-enhanced ultrasound is a real-time imaging technique with the capability of visualizing perfusion patterns.
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